@Crkirby69
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Both pain and pain meds can have an effect on a patient's mood, my husband had a terrible reaction to some pain meds given to him post surgery.
Neck surgery is major and recovery can be slow, without the added burden of mental illness and I suspect you wife would be feeling frustrated in relation to this. (Xrays do not always show a cause for the patients pain.)
When our loved ones are both mentally and physically unwell it can be challenging. Showing love, patience and tenderness is often an intentional choice.
Learning what I could and having an understanding of what was happening by learning about mental illness and the surgical procedure made a difference. Being aware of possible complications that could arise due to MI in relation to his surgery made a difference too (there are well documented poorer outcomes). I do note however the diagnosis came after the surgery in your case.
Letting Mr Darcy know that I am on his team, actively listening to him, encouraging him and advocating for him made a huge difference to us.