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Anyone experience with gut health for depression?

Anyone experience with gut health for depression?

I'm interested to know if anyone here has experience with focusing on gut health as a treatment/aid for depression - either personal experience, close family/friend knowledge, or as a professional/clinician/researcher knowledge.

I've read some publically available studies (but most are at least a few years old, often the case from publication timelines) and they seem to say that gut health helps via serotonin production etc, but the studies about genetic testing for predispositions to things like methylation of foliate or medication-response are not quite to the practical level yet?

But then I know two people who have looked into it as a special area of interest - either due to themselves or a family member with depression or other mood illnesses - who strongly believe and encourage it.

From a physical health perspective, I have nothing to lose by trying it - the treatments won't make me unwell.

But the tests and treatments can cost a lot, and I dont want to waste money! A full genetic test looks to cost me between $600-1,000 😳 and im not sure if/how practical the results will be.

On the other hand, I could try out some of the most common (statistically) solutions without doing the testing??

E.g. ive just started taking probiotics (a 3 month supply) to see if i notice anything better (in mood or in digestion!) - because these are considered good for health anyway, even if not for the hip pocket lol.

E.g. I *could* try taking methylated folate supplements - if the GP/pharmacists say they arent risky to any other part of my health and medications. I trialed high doses of folate 15 years ago (psychiatrist advice) for 3 months but we saw no effect, but apparently current research says that the body may not be methylating it.

So im sitting on the fence for now.

Anyone with thoughts or experience?

7 replies

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In response to: Anyone experience with gut health for depression?

Re: Anyone experience with gut health for depression?

@AlwaysMyself there is research emerging that gut health and mental health are very intertwined. I've never looked at genetic testing, I don't think I have enough information to comment on it. I do take supplements with my regular meds, I don't think it is placebo. I am pretty sure I would at least be low in magnesium if I didn't take it. Folate is also in my migraine supplements, not sure if it helps, it has a ton of stuff in it.

There are naturopath and alternative options like nutrition and dieticians. I found a nutritionist who ordered some bloods and will be looking at my levels in align with optimum levels, she also got me to complete a symptom questionnaire. I haven't started the exercise-nutrition program yet, I could let you know how I go. It wasn't super cheap, but I feel like I haven't been able to find all the answers with modern medicine

In response to: Re: Anyone experience with gut health for depression?

Re: Anyone experience with gut health for depression?

I saw a dietician years ago for insulin resistance.

I haven't had my bloods tested for a while actually (including insulin or diabetes markers), I should add that to next time I see my GP (darn it I saw him only last week lol). In the past the only other abnormality in my bloods is my Vitamin D (which goes up if ive been taking supplements, but otherwise does tend to be very low). I used to get bloods twice per year to monitor for fatigue related causes (vit D, b12, iron, etc).

Tests haven't been able to explain my pain or fatigue either. But it does help that people are more aware of chronic fatigue now post-covid era.

Will be interesting to hear what you program includes and if it helps you @creative_writer . I hope it does!! 🙂

In response to: Re: Anyone experience with gut health for depression?

Re: Anyone experience with gut health for depression?

@AlwaysMyself this nutritionist don’t compare the bloods to the traditional standardised medical range, but to the optimum. Like iron could be in the normal range but not be at the optimum. I think to some degree GPs may recognise this, like my sister’s GP suggested iron supplements twice a week due to her being on the border. She has circulation symptoms even when “normal”.

There can be lots of factors contributing to fatigue, sometimes people need more specialised tests, and sometimes you have to go to a specialist for that. Lots of jumping in hoops

In response to: Re: Anyone experience with gut health for depression?

Re: Anyone experience with gut health for depression?

I have focused on whole foods for 50 years and do believe it is very important for long term mental health and wellbeing. @AlwaysMyself

relatively recently the gut brain hypothesis has been around. I gently include probiotic foods, now that there is more knowledge around, but have always been a yoghurt girl. We love kefir and kombucha, but not everyone is mad on sauerkraut. I just smuggle a bit in. lol. I suspect my good wifey feeding of my ex husband for 16 years helped him come off his Schizophrenia medication, without regress or rehospitalisation.

I do believe it is the long term impact that is important and will do good, rather than worrying too much about the testing.

In response to: Re: Anyone experience with gut health for depression?

Re: Anyone experience with gut health for depression?

The testing is more to guide where to focus efforts.

I like to eat more natural and unprocessed foods, but it can be hard energy-wise with cooking (and cleaning up after cooking). But im currently making an effort to because then I can eat both healthy and foods I dont mind the taste of. I dont like vinegar, so most fermented or pickled foods are a nope for me. But *some* sauerkraut I like - the stuff ive had when in Germany was good, as was the pickled pumpkin I had in Latvia! They dont taste like vinegar or sour or sting. I dont like Indian spices/curries or chilli, so that rules out a *lot* of available-in-Australia healthy premade or quick to make foods. But if I make them at home I can leave out the chilli or change the spice mix.

@Appleblossom that's amazing that your partner has been able to come of their meds and be healthy still! Wow!! Awesome for you supporting them through healthy foods. 🙂

In response to: Anyone experience with gut health for depression?

Re: Anyone experience with gut health for depression?

I am intrigued by this topic, although I haven't found much in the way of peer-reviewed analysis yet. I just happened upon your post today and coincidentally saw an amazing Australian Story last night, which you might enjoy.

In response to: Re: Anyone experience with gut health for depression?

Re: Anyone experience with gut health for depression?

Thanks @Mitzibelle I didnt know Aus Story did a feature on FMT. Just watched it. OMG I cant believe they did that DIY 😮. I first heard about FMT about a year ago I think, but only as something that was just starting to be looked at. I hate the idea of it (mentally), but id be open to it if it was done in a medically-controlled way and didn't cost me much. Id just have to NOT think about what it is!!!!! 🤣🤣🤣

But yeah the basis of the science behind it is why I'm looking into gut health generally. Although not due to antibiotics use, as I tend to avoid them unless a serious need.

Interestingly the post-FMT diet reflects close with what @Appleblossom focuses on with less processed, wholefood, etc. Way to go!

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